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4hv.org :: Forums :: General Science and Electronics
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The little blue pills that sent Abraham Lincoln into a rage

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Tesladownunder
Sat Apr 03 2010, 02:21PM
Tesladownunder Registered Member #10 Joined: Thu Feb 02 2006, 09:45AM
Location: Bunbury, Australia
Posts: 1424
A massive amount of science to the tune of $700M to 1 billion goes into the production of a new blockbuster drug. Big pharma needs to be big. The science is highly regulated and lightyears beyond the "snakeoil" stage. Although one can say that there are a myriad of areas were the science can become slanted we have a clear idea of what constitutes good science in pharmacology. And so does the TGA in Australia and FDA in the USA.
This is an area not frequented by engineers but (if I recall) there is more medical/biological scientific literature out there than the rest of science put together. Just pick up "Science" magazine and you will get an idea. Congratulations if you can understand the biological articles. I can't.
Oncology is an advancing science and we don't have a cure for cancer for everyone yet but for some diseases it cures most people.
And radiotherapy? An anecdote might give you a little perspective. A patient of mine had melanoma of the maxillary sinus (under the cheekbone) treated with radiotherapy 40 years ago. A fatal tumour "cured". She now has developed a completely different tumour (squamous cell carcinoma) in teh same place. She might die from this tumour which would seem likely to be due to the radiation therapy given 40 years ago. We are awaiting the results of a further course of radiotherapy.

Just a little perspective.
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MinorityCarrier
Sat Apr 03 2010, 04:38PM
MinorityCarrier Registered Member #2123 Joined: Sat May 16 2009, 03:10AM
Location: Bend, Oregon
Posts: 312
Read up on BIG pharma Pfizer and their drug labeled 'Bextra'.
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wylie
Thu Apr 08 2010, 12:38PM
wylie Registered Member #882 Joined: Sat Jul 07 2007, 04:32AM
Location:
Posts: 103
Everybody wants a "cure" for cancer, but then people get all uppity about reprogramming our DNA. I don't think we can have it both ways. Seems like an error correction problem with our software that we could just apply a security patch to. But no no no, modifying our DNA is unethical. Oops, is my transhuman showing?

As for treatments, anyone heard more about nanoparticles? Last thing i saw was about gold nanoparticles that if they could get to bind selectively to cancer cells, could then be illuminated with IR to heat up and destroy the cells they're bound to. No poisons, no ionizing radiation, and very minimal collateral cell damage. Quick googling shows some hopeful progress as of 2009, but looks like its only good for skin cancer due to the low penetration depth of IR.

Is there a window of transparency in our tissues anywhere in the spectrum above X-rays? Maybe the nanoparticles could be excited with RF instead of light? We'd prolly just give the patient RF burns though, huh?

At the least, if this treatment makes it through clinical trials skin cancer will be pretty much defeated. Bronzed People Rejoice! (i don't know about any of y'all but i'm as pale as my skin allows. i need to get a new bulb for my metal halide and get my cactus garden going again. its as good as the sun without the hassle of leaving my computer wink plus the cacti are beautiful smile )

sorry for going even further off the original topic. all i know about mercury is that i need to stop leaving FL/CFL tubes around where they can get broken. as for quackery...seems like its alive and well, you just have to slap some "these statements not evaluated by the FDA" smallprint on the bottom of the ad and you're free to sell all the snake oil you want. *sigh*
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Proud Mary
Thu Apr 08 2010, 04:49PM
Proud Mary Registered Member #543 Joined: Tue Feb 20 2007, 04:26PM
Location: UK
Posts: 4992
Post-mortem diagnoses of historical figures are fraught with conjecture and the unverifiable.

Napoléon Bonaparte (1769 – 1821) was claimed to have been poisoned by the English, after neutron activation analysis of a hair sample proved positive for arsenic.

What the test did not reveal was the source of the arsenic, and how the exiled French Emperor came to ingest it.

It is now thought possible that Napoléon died as a consequence of inhaling trimethylarsine gas generated by the biomethylation of the then popular wallpaper pigment, Scheele's Green, (a complex of copper arsenites, and arsenates) by the plant pathogen Microascus brevicaulis which thrived in the tropical climate of St Helena.

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