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Alzheimers caused by prion like proteins?

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LAN_403

Conundrum

Sat Oct 08 2011, 12:18PM

Registered Member #96 Joined: Thu Feb 09 2006, 05:37PM
Location: CI, Earth
Posts: 4061

Hi.

Seems that the latest research suggests that Alzheimers may in fact be triggered by a biochemical cascade of misfolded proteins similar to prions, but substantially less infectious.

This also explains why it seems to run in families, as the same SNP (single nucleotide polymorphism) would be present.
It seems that the protein becomes more sensitive to outside influence so is more likely to misfold, and the odds increase the older the cells get as accumulated damage builds.

-A

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